On April 3, the FDA officially approved maropitant citrate, a generic drug to treat vomiting and motion sickness, for dogs.
Most commonly seen in the brand name drug, Cerenia, maropitant citrate is an antiemetic used in dogs and cats. Until now, the only FDA-approved medication containing maropitant citrate was Cerenia. Their announcement for approval was on January 9, 2007.
Maropitant citrate blocks receptors
Significantly, maropitant citrate is also used to treat acute nausea, such as for dogs recovering from chemotherapy. How maropitant citrate works is as a neurotransmitter inhibitor. Specifically, it blocks the receptors for Substance P, the neurotransmitter that induces vomiting. In this way, Cerenia works as an antiemetic.
Importantly, the FDA approval also stated that the product labeling advises those who handle, administer, or become exposed to maropitant citrate to handle it with care. Specifically, the substance can trigger an allergic reaction on the skin. If this should occur, reported DVM 360, said person should wash the affected area with soap and water immediately. Similarly, maropitant citrate irritates the eyes and requires washing with water. Additionally, anyone who gets the drug in their eyes should seek medical attention.
How should dog owners use maropitant citrate?
For dog owners, having a generic alternative for Cerenia will make this treatment more accessible and more affordable. Particularly while driving, having this treatment on hand is a must for dog owners.
Generally, dogs ingest maropitant citrate orally; it’s available in 16, 24, 60, or 160 mg tablets. Feed your dog a small meal two hours before giving them the medication. After an hour, you can give your dog the tablet.
Another important note: if your dog has suddenly started vomiting frequently, you should call your vet and seek medical help. Only a professional should prescribe any medication to treat or control excessive vomiting, and should also consider your dog’s diet and other factors.
